Cyclobenzaprine: MedlinePlus Drug Information
Drowsiness and confusion can increase the risk of falling. Before taking cyclobenzaprine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. The dosage is based on your medical condition and response to treatment. This medication should only be used short-term (for 3 weeks or less) unless directed by your doctor.
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To do so may increase the chance of serious side effects. Your dose will depend on the severity of your pain and the formulation of cyclobenzaprine you’re using. Cyclobenzaprine is usually taken once daily for only 2 or 3 weeks. Follow your doctor’s dosing instructions very carefully.
Can I take Cyclobenzaprine (Flexeril) if I’m pregnant or breastfeeding?
If you cannot swallow the capsule whole, you may open the capsule and sprinkle the contents over one tablespoon of applesauce. Rinse the mouth orange flexeril to make sure all of the medicine have been swallowed. Do not take more of it and do not take it more often than your doctor ordered.
- The peak concentration varies, depending on what formulation you take.
- Although not all of these side effects may occur, if they do occur they may need medical attention.
- In light of these findings, therapy with FLEXERIL in the elderly should be initiated with a 5 mg dose and titrated slowly upward.
- Cyclobenzaprine is used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries.
Do not start, stop, or change the dose of any drug without checking with your doctor. Further research is needed to conclusively address this question. The possible benefit of questionable magnitude has led us to rate this topic yellow (unclear benefits). Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. People might also use Flexeril as a way to come down from Stimulant drugs, such as Cocaine or Adderall.
Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Cyclobenzaprine (Flexeril) is structurally similar to TCAs and, as such, demonstrates significant anticholinergic side effects. It differs from the TCA amitriptyline by only one double bond.
Cyclobenzaprine relieves skeletal muscle spasms of local origin without interfering with muscle function. In preclinical research, cyclobenzaprine reduced skeletal muscle hyperactivity. Research indicates that it primarily acts within the central nervous system in the brain stem. Cyclobenzaprine comes as a tablet and an extended-release capsule to take by mouth. The tablet is usually taken with or without food three times a day. The extended-release capsule is usually taken with or without food once a day.
If cyclobenzaprine is beingmisused, however, the person may continue to take the medication for much longer and may increase their dose too high, which could lead to dangerous side effects and overdose. A post-marketing surveillance program was carried out in 7607 patients with acute musculoskeletal disorders, and included 297 patients treated with FLEXERIL 10 mg for 30 days or longer. The overall effectiveness of FLEXERIL was similar to that observed in the double-blind controlled studies; the overall incidence of adverse effects was less (see ADVERSE REACTIONS). The plasma concentration of cyclobenzaprine is increased in the elderly (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Elderly).
Enhancing Healthcare Team Outcomes
Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Because of the possibility of higher blood levels in the elderly as compared to younger adults, use of cyclobenzaprine extended-release capsules is not recommended in the elderly. Appropriate studies have not been performed on the relationship of age to the effects of cyclobenzaprine extended-release capsules in the pediatric population. While the addictiveness of cyclobenzaprine is being debated, anyone exhibiting problematic patterns of substance use can benefit from addiction treatment. This is especially true if someone has been engaging in polydrug use with cyclobenzaprine and other substances. However, the half-life of immediate-release cyclobenzaprine is 18 hours on average, with a range of 8-37 hours.
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Sometimes, muscle relaxants like cyclobenzaprine are used “off-label” to treat conditions they’re not approved for, such as fibromyalgia. Cyclobenzaprine is a drug prescribed to treat pain and discomfort. This page will go over its side effects, drug interactions, and treatment for misuse.
It belongs to a group of medications called muscle relaxants. Improvements in low back pain symptoms were present at all recorded time points, but the authors noted more of an effect size in the first four days of treatment. Because adverse effects would be present beyond the first few days, any optimum effectiveness of treatment would likely be short.